New UQ Method Integrates Joint Aleatoric and Epistemic Uncertainties

Leonhard F. Feiner, Manuel Nickel, Martin Menten, Laurin Lux, Rickmer Braren, Daniel Rueckert, Georgios Kaissis, Raphael Rehms, Johannes Paetzold· August 26, 2026 View original

Key takeaways

  • Jointly modeling aleatoric and epistemic uncertainties enhances deep learning reliability.
  • A low-rank plus diagonal covariance structure efficiently captures output correlations.
  • This unified approach supports robust downstream analyses like sampling.
  • The method improves UQ in high-dimensional tasks like image inpainting and depth estimation.

Who benefits

HealthcareAutonomous VehiclesManufacturingRemote SensingMedia & Entertainment

Summary

This paper introduces a novel approach for Uncertainty Quantification (UQ) that jointly integrates aleatoric (data noise) and epistemic (model confidence) uncertainties in high-dimensional regression tasks. The method uses a low-rank plus diagonal covariance structure to capture essential output correlations efficiently, leading to more reliable deep learning predictions.

This research addresses a critical challenge in deep learning: enhancing the reliability of predictions, especially in applications with high-dimensional output spaces like medical image segmentation or restoration. The paper focuses on the dual nature of uncertainty – aleatoric, which stems from inherent data noise, and epistemic, which reflects the model's confidence or knowledge gaps. Traditionally, these are often treated separately, limiting the transparency and robustness of predictions. The proposed novel approach explicitly combines both types of uncertainties into a unified second-order distribution. To manage the computational burden of high-dimensional outputs, it approximates the resulting joint uncertainty using a low-rank plus diagonal covariance structure, effectively capturing essential output correlations. This method supports robust downstream analyses such as sampling and log-likelihood evaluation and includes stabilization strategies for efficient training and inference, demonstrating superior UQ performance in tasks like image inpainting, colorization, optical flow, and depth estimation.

Why it matters

Professionals in fields relying on high-dimensional deep learning outputs can achieve more trustworthy and robust model predictions by explicitly accounting for both data noise and model confidence, crucial for critical applications like medical imaging or autonomous systems.

How to implement this in your domain

  1. 1Assess current deep learning models for high-dimensional regression tasks to identify where UQ could be improved.
  2. 2Investigate integrating joint aleatoric and epistemic uncertainty modeling into new or existing projects.
  3. 3Explore using low-rank plus diagonal covariance structures to efficiently capture output correlations in UQ.
  4. 4Apply the proposed stabilization strategies during training and inference to enhance UQ efficiency.
  5. 5Benchmark the reliability and robustness of predictions using this joint UQ approach against single-uncertainty methods.

Original post by Leonhard F. Feiner, Manuel Nickel, Martin Menten, Laurin Lux, Rickmer Braren, Daniel Rueckert, Georgios Kaissis, Raphael Rehms, Johannes Paetzold

"arXiv:2608.24518v1 Announce Type: new Abstract: Uncertainty Quantification (UQ) plays a vital role in enhancing the reliability of deep learning model predictions, especially in scenarios with high-dimensional output spaces. This paper addresses the dual nature of uncertainty --…"

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Originally posted by Leonhard F. Feiner, Manuel Nickel, Martin Menten, Laurin Lux, Rickmer Braren, Daniel Rueckert, Georgios Kaissis, Raphael Rehms, Johannes Paetzold on X · view source

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