AI System Detects H. pylori from Biopsy Reports

Yufan Wang, Anit Kumar Sahu, Yan Fei Ng, Daniel Kang, Shayan Vassef, Soorya Ram Shimgekar, Koustuv Saha, Piyum Zonooz, Navin Kumar, Chee Leong Cheng, Li Yan Khor· July 8, 2026 View original

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Summary

A multi-agent system called nMAS accurately extracts Helicobacter pylori infection evidence from gastric biopsy reports, improving efficiency and traceability compared to manual review. The system achieved 98.61% accuracy in a pilot study.

Researchers have developed the Nimblemind Multi-Agent System (nMAS) to automate the detection of Helicobacter pylori infection from gastric biopsy pathology reports. This system is designed to overcome the challenges of extracting information from heterogeneous coded and free-text fields, which often require complex contextual interpretation. In a pilot evaluation using 54 de-identified reports, nMAS demonstrated high accuracy, correctly classifying 98.61% of feature-case decisions across various fields related to H. pylori positivity and associated gastritis. While its predictive performance was comparable to other methods, nMAS's key contribution lies in its workflow integration and traceability, providing unified report-level outputs with supporting source sentences. This approach significantly reduces the time required for review, potentially saving substantial staff-hours and costs in healthcare settings.

Why it matters

Healthcare professionals can leverage AI to streamline the identification of critical medical conditions from complex clinical reports, improving diagnostic efficiency and patient care.

How to implement this in your domain

  1. 1Evaluate existing clinical report processing workflows for manual bottlenecks.
  2. 2Pilot AI-driven text extraction tools for specific diagnostic criteria.
  3. 3Collaborate with AI developers to customize models for specialized medical terminology.
  4. 4Implement a verification process for AI-extracted data to ensure accuracy and compliance.

Who benefits

HealthcarePharmaceuticalsMedical Devices

Key takeaways

  • nMAS uses a multi-agent system to extract H. pylori evidence from biopsy reports.
  • It achieved high accuracy (98.61%) in a pilot study.
  • The system offers improved workflow integration and traceability.
  • Significant time and cost savings are possible compared to manual review.

Original post by Yufan Wang, Anit Kumar Sahu, Yan Fei Ng, Daniel Kang, Shayan Vassef, Soorya Ram Shimgekar, Koustuv Saha, Piyum Zonooz, Navin Kumar, Chee Leong Cheng, Li Yan Khor

"arXiv:2607.06435v1 Announce Type: new Abstract: Data from Singapore indicated that about 31% of the population had evidence of Helicobacter pylori infection. Persistent H. pylori infection is associated with chronic active gastritis and peptic ulcer disease, and its eradication i…"

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Originally posted by Yufan Wang, Anit Kumar Sahu, Yan Fei Ng, Daniel Kang, Shayan Vassef, Soorya Ram Shimgekar, Koustuv Saha, Piyum Zonooz, Navin Kumar, Chee Leong Cheng, Li Yan Khor on X · view source

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