Disaggregated Prefill and Decode for LLM Inference on HyperPod

Xuan Lu· July 10, 2026 View original

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Summary

This post demonstrates implementing Disaggregated Prefill and Decode (DPD) with vLLM on Amazon SageMaker HyperPod. It uses the HyperPod Inference Operator to optimize LLM inference.

The article focuses on a technical optimization for Large Language Model (LLM) inference, specifically demonstrating the implementation of Disaggregated Prefill and Decode (DPD). This technique is shown in conjunction with vLLM, a high-performance inference engine, deployed on Amazon SageMaker HyperPod. The core of the demonstration involves utilizing the HyperPod Inference Operator to effectively manage and execute this optimized inference process. The goal is to improve the efficiency and scalability of LLM serving by separating the prefill and decode phases of token generation.

Why it matters

Professionals can learn advanced techniques to optimize LLM inference performance and cost, which is crucial for deploying large models efficiently in production.

How to implement this in your domain

  1. 1Understand the concepts of LLM prefill and decode phases.
  2. 2Explore the benefits of disaggregated prefill and decode (DPD) for inference.
  3. 3Learn how to integrate vLLM for high-performance LLM serving.
  4. 4Utilize Amazon SageMaker HyperPod and its Inference Operator for deployment.
  5. 5Implement DPD to optimize LLM inference efficiency and scalability.

Who benefits

TechAI/ML StartupsCloud ServicesResearch

Key takeaways

  • Disaggregated Prefill and Decode (DPD) optimizes LLM inference.
  • vLLM is a powerful engine for high-performance LLM serving.
  • SageMaker HyperPod provides infrastructure for advanced LLM deployments.
  • The HyperPod Inference Operator facilitates DPD implementation.

Original post by Xuan Lu

"In this post, we show how to implement DPD with vLLM on Amazon SageMaker HyperPod using the HyperPod Inference Operator."

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Originally posted by Xuan Lu on X · view source

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