CardioState-JEPA Learns Shared Cardiac Representation Across Modalities.

Hamza Shafiq, Hung Manh Pham, Bin Zhu, Pan Zhou, Jun Hu, Aaqib Saeed· August 14, 2026 View original

Key takeaways

  • CardioState-JEPA creates a unified cardiac representation from ECG, PPG, and PCG.
  • The model uses a delay aligner to handle temporal offsets between signals.
  • It significantly improves performance on various cardiac diagnostic tasks.
  • Multi-modal learning can reduce reliance on scarce synchronized and labeled medical data.

Who benefits

HealthcareMedical DevicesPharmaceuticalsWearable Tech

Summary

This paper introduces CardioState-JEPA, a cardiac foundation model that learns a single shared representation from ECG, PPG, and PCG signals using a physiology-aware joint-embedding predictive architecture. It leverages a learned delay aligner to handle temporal offsets and improves performance across 25 downstream cardiac tasks.

Existing cardiac foundation models typically focus on a single sensing modality, failing to exploit the shared physiological information present across different cardiac signals like Electrocardiography (ECG), Photoplethysmography (PPG), and Phonocardiography (PCG). This research presents CardioState-JEPA, a novel cardiac foundation model designed to learn a unified, shared representation from these heterogeneous signals. It employs a physiology-aware joint-embedding predictive architecture. CardioState-JEPA maps diverse waveforms into a common token space and processes them with a shared Transformer encoder. It learns by predicting masked latent cardiac states, focusing on shared physiology rather than sensor-specific appearances. To address the inherent temporal delays between electrical, mechanical, and hemodynamic events, the model incorporates a learned delay aligner. The training strategy first learns within-modality structure from abundant unimodal data, then aligns modalities using scarcer paired data. Evaluation across 25 downstream tasks shows significant improvements in classification and detection for PPG, PCG, and ECG compared to self-supervised baselines, matching or exceeding models trained with clinical text or supervised labels.

Why it matters

This breakthrough in multi-modal cardiac AI can lead to more accurate and comprehensive diagnostic tools, improving patient care and reducing reliance on extensive labeled datasets.

How to implement this in your domain

  1. 1Explore integrating multi-modal cardiac data (ECG, PPG, PCG) into existing diagnostic pipelines.
  2. 2Investigate the use of foundation models like CardioState-JEPA for developing new cardiac monitoring devices.
  3. 3Leverage the concept of delay-aware cross-modal learning for other physiological signal integration.
  4. 4Consider applying similar self-supervised learning approaches to medical data where labeled datasets are scarce.

Original post by Hamza Shafiq, Hung Manh Pham, Bin Zhu, Pan Zhou, Jun Hu, Aaqib Saeed

"arXiv:2608.12944v1 Announce Type: new Abstract: Electrocardiography (ECG), photoplethysmography (PPG), and phonocardiography (PCG) provide complementary views of the same cardiac cycle, yet existing cardiac foundation models are trained for a single sensing modality, leaving the…"

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Originally posted by Hamza Shafiq, Hung Manh Pham, Bin Zhu, Pan Zhou, Jun Hu, Aaqib Saeed on X · view source

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