New Metric Assesses AI Explanation Consistency for Medical Imaging Fairness

Kerol Djoumessi, Philipp Berens· August 20, 2026 View original

Key takeaways

  • Fairness in medical AI should extend beyond predictive performance to include explanation consistency.
  • The Explanation Consistency Score (ECS) quantifies how similarly AI models use visual evidence across subgroups.
  • Predictive disparities do not necessarily imply inconsistent explanations.
  • Evaluating both predictive fairness and explanation consistency offers a more comprehensive view of AI behavior.

Who benefits

HealthcareMedical TechnologyAI/ML DevelopmentRegulatory Compliance

Summary

This work introduces the Explanation Consistency Score (ECS) to quantify how consistently AI models use visual evidence across different demographic groups in medical imaging. Applied to diabetic retinopathy screening, it shows that while predictive performance varies, explanation consistency can remain high, suggesting complementary aspects of fairness.

Evaluating fairness in medical imaging AI typically focuses on how well models perform across different demographic subgroups. However, this approach doesn't reveal whether the AI relies on the same visual cues or evidence when making predictions for various groups. This paper addresses that gap by proposing a new metric called the Explanation Consistency Score (ECS). The ECS uses Jensen-Shannon divergence to measure the similarity of attribution maps, which highlight the parts of an image an AI focuses on, across different demographic subgroups. The researchers applied this metric to a case study involving diabetic retinopathy screening. Their experiments revealed that while the AI's predictive performance did show differences across ethnic groups, the explanation consistency remained relatively high and did not strongly correlate with these performance disparities. This suggests that predictive fairness and explanation consistency are distinct but equally important dimensions of AI behavior, advocating for a broader approach to fairness evaluations beyond just predictive accuracy.

Why it matters

Ensuring AI models are fair and trustworthy in critical applications like healthcare requires understanding not just what they predict, but how they arrive at those predictions across diverse populations. This new metric provides a crucial tool for auditing AI transparency and bias.

How to implement this in your domain

  1. 1Integrate the Explanation Consistency Score (ECS) into AI model evaluation pipelines for medical imaging applications.
  2. 2Conduct fairness audits on existing AI models using ECS to identify inconsistencies in visual evidence utilization across demographic groups.
  3. 3Develop training strategies or regularization techniques aimed at improving explanation consistency alongside predictive performance.
  4. 4Collaborate with ethicists and domain experts to interpret ECS results and inform responsible AI deployment in healthcare.

Original post by Kerol Djoumessi, Philipp Berens

"arXiv:2608.18759v1 Announce Type: new Abstract: Fairness in medical imaging is commonly evaluated through subgroup performance metrics, yet it remains unclear whether models rely on consistent visual evidence across demographic groups. This work introduces the Explanation Consist…"

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